| Home | Visitor | Venue | Time | Final Score | Game Details | |||||
| Friday September 03 2010 | ||||||||||
| Serbian White Eagles | North York Astros | Centennial Stadium | 8:00 pm | - | ||||||
| Portugal FC | York Region Shooters | Lamport Stadium | 8:00 pm | - | ||||||
| London City | Brampton Lions | Cove Road | 8:40 pm | - | ||||||
| Sunday September 05 2010 | ||||||||||
| Brampton Lions | Serbian White Eagles | Victoria Park | 3:00 pm | - | ||||||
| Milltown FC | TFC Academy | Bishop Reding SS | 4:00 pm | - | ||||||
| York Region Shooters | North York Astros | St. Joan Of Arc | 6:00 pm | - | ||||||
| Brantford Galaxy | London City | Lions Park | 7:00 pm | - | ||||||
| Wednesday September 08 2010 | ||||||||||
| St. Catharines Wolves | Portugal FC | Club Roma | 8:00 pm | - | ||||||